We are often led to believe that anything ‘whole’ is what’s good for us – whole food, wholesomeness, wholemeal bread, wholegrain rice… Now, this may be true when trying to choose a healthy diet, but it’s certainly not the case when it comes to Faecal Microbiota Transplant.
There are a number of reasons that we don’t use implants of whole, raw faeces at Taymount. Whole stool contains many things that a recipient of a Faecal Microbiota Transplant would not want. In fact, a more fitting term might actually be ‘Gut Flora Transplant’ or GFT. This really tells you that the only thing needed in this transplant is the gut microbiota.
What we don’t need in our FMT implants are….
Donor epithelial cells; (skin-like cells which slough off the inside of the donor’s digestive tract lining, everything from the cells in the mouth and stomach, to the intestinal cells and cells from the rectum and anus).
Donor mucus; mucus is the protective and lubricating substance that is secreted by the donor from the whole area of the digestive tract, once again, from the mouth to the anus. Mucus helps to trap and hold toxins, waste products and other materials on their journey through the donor’s digestive tract; it would serve no purpose for the recipient to receive this.
Food wastes; undigested particles of food from the donor’s food can be found in their stool and, particularly if the donor does not chew thoroughly, there could be large-ish compound molecules of foods which might even cause the recipient to have a food-intolerance reaction, if foods that they cannot tolerate are present in the whole stool implant.
Hormones; water-soluble hormones are sometimes found in stool. This can be problematical if for example, your recipient is a female at the top end of the maximum female levels of testosterone (known as the male hormone), and the donor is a man at the top end of the male spectrum of that hormone; the female recipient would not benefit from getting another dose of testosterone in her FMT procedure, which might take her over the female desirable limit, as an unwanted side-effect of her FMT.
Biliary waste products; the human gastro-intestinal tract is designed to be an exit-route for the liver to dump processed wastes out of the body. The liver could be described as the master chemical processing organ and it is the function of the liver to detox, break down and render harmless, all manner of bio-chemical insults, toxins and metabolic wastes found in the body. The liver will dump such materials out through the bile flow into the cholescyst (gall bladder) and out through the duodenum and intestines, thereby leaving the body with the bowel movements. There would be little point in transferring such waste materials to another body; the large intestine of the recipient may offer opportunities to absorb this material, which would end up in the recipient’s liver for re-processing and re-dumping. This presents an unnecessary detoxification burden for the host’s liver and biliary system.
Patients at Taymount can rest assured that the systems we have in place ensure that all unnecessary material is removed from our implants and that we only deliver the vital, preserved, microbial content of the donor stool.